Aim: The aim of the present study was to investigate the effect of high-intensity interval training (HIIT) and nanocurcumin consumption on the regulation of glucose metabolism in obese and overweight women.
Methods: Forty obese and overweight women (BMI=31.09 ± 2.77) were divided into five groups of 8: high-intensity interval training (HIIT), nanocurcumin (NanoC), high-intensity interval training + nanocurcumin (HIIT + nanoC), placebo (Pl), and control. The HIIT training groups ran for eight weeks, three sessions per week, at an intensity of 80% of maximum heart rate(HRmax).The nanocurcumin groups received 80 mg of it daily for eight weeks. HbA1c, fasting glucose, insulin resistance index(HOMA-IR), and time to exhaustion (TTE) were measured before and after the intervention and analyzed using two-way analysis of variance (ANOVA).
Results: The results showed that glucose and HOMA-IR levels were significantly different between the study groups (p<0.001). The greatest reduction in serum glucose(14.72%) and HOMA-IR(47.54%) was observed in the HIIT+nanoC group compared to the NanoC and PL groups (p<0.001, for all comparisons). Also, HbA1c levels in the HIIT+nanoC group had the greatest significant reduction compared to both the HIIT (p=0.001) and NanoC (p=0.001) groups.In addition, TTE in the HIIT+NanoC group was significantly increased compared to the NanoC, HIIT, and PL groups(p<0.001).
Conclusion: HIIT training and nanocurcumin supplementation as non-pharmacological interventions had beneficial effects on glucose control, especially on insulin resistance in obese and overweight women. The combination of these two interventions as well as HIIT training had greater effects on improving glucose metabolism than nanocurcumin consumption alone.
Babaei, T. , Mohamadzadeh Salamat, K. and Etemad, Z. (2025). The Interactive effect of High Intensity Interval training and nanocurcumin consumption on regulating glucose metabolism in obese and overweight women. Research in Exercise Nutrition, 4(4), 33-44. doi: 10.22034/ren.2025.144495.1129
MLA
Babaei, T. , , Mohamadzadeh Salamat, K. , and Etemad, Z. . "The Interactive effect of High Intensity Interval training and nanocurcumin consumption on regulating glucose metabolism in obese and overweight women", Research in Exercise Nutrition, 4, 4, 2025, 33-44. doi: 10.22034/ren.2025.144495.1129
HARVARD
Babaei, T., Mohamadzadeh Salamat, K., Etemad, Z. (2025). 'The Interactive effect of High Intensity Interval training and nanocurcumin consumption on regulating glucose metabolism in obese and overweight women', Research in Exercise Nutrition, 4(4), pp. 33-44. doi: 10.22034/ren.2025.144495.1129
CHICAGO
T. Babaei , K. Mohamadzadeh Salamat and Z. Etemad, "The Interactive effect of High Intensity Interval training and nanocurcumin consumption on regulating glucose metabolism in obese and overweight women," Research in Exercise Nutrition, 4 4 (2025): 33-44, doi: 10.22034/ren.2025.144495.1129
VANCOUVER
Babaei, T., Mohamadzadeh Salamat, K., Etemad, Z. The Interactive effect of High Intensity Interval training and nanocurcumin consumption on regulating glucose metabolism in obese and overweight women. Research in Exercise Nutrition, 2025; 4(4): 33-44. doi: 10.22034/ren.2025.144495.1129
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